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Somatropin belongs to a class of drugs known as growth stimulants. Somatropin is a synthetic version of growth hormone. Growth hormone is made naturally in our bodies by the pituitary gland. This medication is used to manage HIV wasting (a metabolic disorder resulting in severe weight loss seen in people with HIV). It works by stimulating an increase in lean body mass (i.e., muscle mass).

This medication may be available under multiple brand names and/or in several different forms. RELATED PRODUCTS

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Serostim (somatropin) is an expensive drug used to treat HIV-wasting syndrome. It is slightly more popular than comparable drugs. Serostim is only available as a brand drug. It is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.

Indications for: SEROSTIM

HIV patients with wasting or cachexia to increase lean body mass and weight, and improve physical endurance.

Adult Dosage:

Give by SC inj once daily at bedtime. Rotate inj sites. <35kg: 0.1mg/kg. 35–45kg: 4mg. 45–55kg: 5mg. >55kg: 6mg. Risk factors for adverse effects (eg, glucose intolerance): initially 0.1mg/kg every other day.

Children Dosage:

Not established; see full labeling.

SEROSTIM Contraindications:

Acute critical illness due to surgical complications or multiple accidental trauma or those with acute respiratory failure. Active malignancy. Active proliferative or severe non-proliferative diabetic retinopathy.

SEROSTIM Warnings/Precautions:

Increased mortality in those with acute critical illness (see Contraindications). Use only under guidance of a physician trained in HIV management. HIV patients should be maintained on antiretroviral therapy. Glucose intolerance. Diabetes. Perform baseline and periodic funduscopic evaluation for intracranial hypertension; discontinue if papilledema occurs; may restart at lower dose after resolution. Monitor for development, progression, or recurrence of neoplasms. Discontinue if carpal tunnel syndrome persists after dosage reduction. Turner syndrome. Elderly. Pregnancy (Cat.B). Nursing mothers

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