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What is hydromorphone?
Hydromorphone oral tablet is a prescription drug that’s available as the brand-name drug Dilaudid (immediate release). These tablets are also available as generic drugs. Generic drugs usually cost less. In some cases, they may not be available in every strength or form as the brand-name versions.
Hydromorphone also comes in the following forms:
oral liquid solution
injectable solution
high-potency injectable solution
The injectable solutions are only given by a healthcare professional.
Hydromorphone oral tablet is a controlled substance. This means this drug has a risk of misuse and may cause dependence.
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Why it’s used
Hydromorphone oral tablet is used to treat severe pain that isn’t controlled by other treatments. The extended-release tablet is used for people who need daily, around-the-clock pain treatment.
This drug may be used as part of a combination therapy. This means you may need to take it with other medications.
How it works
Hydromorphone oral tablet belongs to a class of drugs called opioid analgesics. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.
It isn’t known exactly how this drug works to ease pain. It may reduce pain by acting on certain opioid receptors in the brain and spinal cord, which make up your central nervous system.
The hydromorphone dosage your doctor prescribes will depend on several factors. These can include:
- the type and severity of the condition you’re using hydromorphone to treat
- your age
- the form of hydromorphone you take
- other medical conditions you may have
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Typically, your doctor will start you on a low dosage and adjust it over time to reach the dosage that’s right for you. They’ll ultimately prescribe the smallest dosage that provides the desired effect.
Be sure to check accuracy when prescribing, dispensing, and administering this drug. Dosing errors caused by confusion between “mg” and “mL” can result in accidental overdose and death.
The following information describes dosages that are commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to suit your needs.
Forms and strengths
Generic: Hydromorphone HCL
- Form: oral tablet
- Strengths: 2 milligrams (mg), 4 mg, 8 mg
- Form: extended-release oral tablet (24-hour abuse deterrent)
- Strengths: 8 mg, 12 mg, 16 mg, 32 mg
Brand: Dilaudid
- Form: oral tablet
- Strengths: 2 mg, 4 mg, 8 mg
- Form: extended-release oral tablet
- Strengths: 8 mg, 12 mg, 16 mg, 32 mg
Dosage for severe pain
Adult dosage (ages 18–64 years)
- Oral tablet: Typical starting dosage is 2–4 mg once every 4–6 hours.
- Extended-release oral tablet: For use only in people who are opioid tolerant.
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Side Effects
Nausea, vomiting, constipation, lightheadedness, dizziness, drowsiness, sweating, flushing, or dry mouth may occur. Some of these side effects may decrease after you have been using this medication for a while. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
To prevent constipation, eat dietary fiber, drink enough water, and exercise. You may also need to take a laxative. Ask your pharmacist which type of laxative is right for you.
To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.
Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
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