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Buy Follistatin Online is a full-sized synthetic analogue of naturally occurring Follistatin. It neutralizes the effects of myostatin, activin, and follicle stimulating hormone (FSH). In animal studies, these actions lead to increased muscle mass (both hypertrophy and hyperplasia), reduced scar formation, and inhibited certain inflammatory responses. Follistatin-344 can be altered by the body to produce other variants of Follistatin.
What Is Follistatin 344? Follistatin (FST) 344 is a synthetic version of the naturally occurring human follistatin protein. Follistatin is found in nearly all tissues of higher animals and comes in two separate isoforms as a result of alternative gene splicing. Its primary biological function is neutralization of proteins in the TGF-beta superfamily. It has particularly potent neutralizing effects on activin, myostatin, and follicle-stimulating hormone.
Follistatin in Esophageal Cancer Research has identified bone morphogenic protein (BMP) as a causative agent in the transition of normal esophageal tissue to Barrett’s esophagus, a precursor to cancer. It appears that acid reflux over-activates BMP in the esophagus and that counteracting this over-activation, such as through follistatin supplementation, could prevent the development of Barrett’s esophagus in the first place. BMP misregulation is actually a common theme in a number of different cancers. For instance, impaired BMP signaling is important in the progression of colon cancer. More research clearly needs to be done, particularly in animal models, to better quantify how follistatin can be used in the treatment and prevention of BMP misregulation. Follistatin Research and Cancer Treatment Researchers have found that follistatin active in a number of different tumors, and that its effects are not just limited to breast cancer and liver carcinoma. With better understanding of how follistatin works, it is hoped that a number of clinical applications for the protein can be developed.
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Currently, follistatin expression has been associated with improved survival in breast cancer, but shortened survival in lung, ovarian, and gastric cancers. It is hoped that understanding these differences in how the protein affects survival will allow for the development of treatment adjuvant tailored to specific types of cancer. Follistatin research may even form the basis of a cancer preventative or vaccine, slowing rates of metastasis and improving long-term survival.