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Buy 5-Amino-1MQ (60 Capsules) Online is a small molecule that blocks the activity of the enzyme called nicotinamide N-methyltransferase (NNMT). NNMT is a very important component in metabolism and energy and is predominantly active in fat tissue. By blocking NNMT, 5-amino-1MQ stimulates an increase in nicotinamide adenine dinucleotide (NAD+), a cofactor that is central to cellular metabolism, thereby increasing metabolic rate and activating a gene called sirtuin-1 (SIRT1). SIRT1 is also known as the “longevity gene” because of its role in reducing the risk of diabetes, obesity, metabolic syndrome, atherosclerosis and other forms of cardiovascular disease, kidney disease, liver disease, neurodegeneration, and cancer. Research in mice given 5-amino-1MQ showed a 7% reduction in body mass without any changes in food intake, compared to controls. Research has shown that decreasing NNMT may help shrink fat cells and reduce the size of fat deposits.
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Excess weight and obesity can be difficult to reverse or treat effectively. This can be due to changes in metabolism that reduce the ability of the body’s fat stores to break down and become available as a source of energy. As a result, people affected by excess weight and obesity may find it harder to lose weight over time regardless of diets, eating styles or activity patterns. As fat cells grow larger, they begin to overproduce an enzyme called NNMT. This enzyme acts to slow down fat cell metabolism (fat burning). This slowdown makes it harder for these cells to burn accumulating fat. As fat tissue grows and more NNMT is produced, greater amounts of hormones and pro-inflammatory signals are produced that are responsible for weight gain and other chronic diseases such as type 2 diabetes and cardiovascular disease. Researchers at the University of Texas discovered a molecule that blocks this metabolic slowdown in white fat cells caused by excess NNMT. By blocking this metabolic slowdown, they were able to increase the metabolism within the white fat cells. Researchers add that by inhibiting the NNMT enzyme, we can increase fat cell metabolism and reduce the size of white fat deposits. We lose weight because we are treating a root cause of obesity and related metabolic disease.